Start by making the sauce: Combine melted butter, hot sauce, Worcestershire sauce, and garlic powder in a bowl. Stir until smooth and set aside.
Preheat your air fryer to 360°F for about 5 minutes.
Mix salt, garlic powder, and pepper in a small bowl. Toss the cauliflower florets in this seasoning mix, ensuring an even coat. Add the beaten egg to the cauliflower and mix well until all pieces are coated.
In a separate bowl, combine the breadcrumbs and Parmesan cheese. Dip each cauliflower floret into this breadcrumb mixture, making sure each piece is well-covered. Shake off any excess.
Lightly spray the breaded cauliflower with cooking spray to avoid dry spots. Be thorough, as dry breading can cause issues in the air fryer.
Prepare your air fryer basket or tray by spraying it with oil or lining it with a perforated silicone mat or parchment paper. Place the cauliflower in a single layer inside the basket/tray.
Cook the cauliflower in the air fryer at 360°F for 8 minutes. Flip the pieces gently and spray any dry spots with oil. Continue air frying for an additional 3-5 minutes, or until the cauliflower reaches your desired level of crispiness and golden brown color.
Once cooked, toss the cauliflower in the prepared buffalo sauce.
For an extra crispy finish, you can air fry the sauced cauliflower at 380°F for an additional 3 minutes, or until it reaches your preferred texture. Garnish with chopped parsley, cilantro, and/or green onion if desired.